Prior exposure to stress delays extinction but does not modify reinstatement of nicotine-induced conditioned place preference. - Sistema de Solicitudes - Universidad San Buenaventura

Título Artículo	Prior exposure to stress delays extinction but does not modify reinstatement of nicotine-induced conditioned place preference. Artículo de Revista
Parte de	Psychology & Neuroscience psychology & neuroscience Pagina(s) 53-57
Autor(es)	Leão, Rodrigo M. (Autor) Cruz , Fábio C. (Autor)
Idioma	Inglés;
Nota(s)	Autores: Rodrigo M. Leao; Fabio C. Cruz; Cleopatra S. Planeta.
Resumen	Studies in humans suggest that exposure to stress is related to relapse tobacco use. The reinstatement of condictioned place preference (CCP) provides a simple, noninvasive and easy approach to investigate the mechanisms for drug relapse. The present study investigated wheter repeated exposure to stress could change the extincition and reinstatment of nicotine-induced CCP. Adult male Wistar were exposed to restraint-stress for 2 hours/daily for 7 days, while the control group was left undistrubed to the compartmente paired with its injections during contidioning (16mg/kg s.c.; four drug sessions.